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Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein
Ruđer Bošković Institute, 2021. urn:nbn:hr:241:733364
Tomić, Draško

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Dataset: covid-19_results_mar_dec_2020.zip, 1.22 GB
Access Condition: Open access

Documentation: efficacy_of_fda_approved_hiv_drugs_on_sars-cov-2.txt, 720 bytes
Access Condition: Open access
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Methodology description (English)

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Cite this document

Tomić, D. (2021). Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein [Data set]. https://urn.nsk.hr/urn:nbn:hr:241:733364.

Tomić, Draško. Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein. Institut Ruđer Bošković, 2021. 10 Dec 2024. https://urn.nsk.hr/urn:nbn:hr:241:733364.

Tomić, Draško. 2021. Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein. Institut Ruđer Bošković. https://urn.nsk.hr/urn:nbn:hr:241:733364.

Tomić, D. 2021. Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein. Institut Ruđer Bošković. [Online]. [Accessed 10 December 2024]. Available from: https://urn.nsk.hr/urn:nbn:hr:241:733364.

Tomić D. Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein. [Internet]. Institut Ruđer Bošković: , HR; 2021, [cited 2024 December 10] Available from: https://urn.nsk.hr/urn:nbn:hr:241:733364.

D. Tomić, Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein, Institut Ruđer Bošković, 2021. Accessed on: Dec 10, 2024. Available: https://urn.nsk.hr/urn:nbn:hr:241:733364.

Title (english)Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein
AuthorDraško Tomić
Institut Ruđer Bošković
Ruđer Bošković Institute
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Medical Biochemistry
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Bioinformatics
Abstract (english)
These results were obtained using the Vini in silico model of cancer in the period from March to December 2020. The efficacy of 49 FDA-approved antiviral drugs on SARS-CoV-2 spike glycoprotein was analyzed. Based on the fact that HIV drugs showed the highest efficacy, the efficacy of their double and triple combinations was further calculated.
Methods (english)These results were obtained using the Vini in silico model of cancer in the period from March to December 2020. The efficacy of 49 FDA-approved antiviral drugs on SARS-CoV-2 spike glycoprotein has analyzed with the Vini in silico model of cancer. Based on the fact that HIV drugs showed the highest efficacy, the efficacy of their double and triple combinations was further calculated. Finally, 10 most effective HIV drug combinations were finally examined on their possible adverse effects with Medscape and Lexicomp software.
Keywords (english)
Languageenglish
URN:NBNurn:nbn:hr:241:733364
Publication2021-01-18
GeolocationCroatia
ProjectNumber: KK.01.1.1.01.009
Title (croatian): Napredne metode i tehnologije u znanosti o podatcima i kooperativnim sustavima-DATACROSS
Acronym: DATACROSS
Leader: Sven Lončarić; Petrović Ivan
Jurisdiction: eu
PublisherInstitut Ruđer Bošković
Ruđer Bošković Institute
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2021-03-01 13:35:10